HOME > mice > ED-L2-Cre/+ Elovl1 flox/+ mice
Strain Detail: ED-L2-Cre/+ Elovl1 flox/+ mice
| Strain information |
| Resource No. |
nbio480 |
| Strain name |
ED-L2-Cre/+ Elovl1 flox/+ |
| Strain Nomenclature |
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| Common name/Synonyms |
Elovl1cKO |
| Strain types |
mutant |
| Background strain |
C57BL/6JmsSlc |
| Institution |
Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido University |
| Developer |
Akio Kihara |
| Depositor |
Akio Kihara |
| Conditions of distribution |
Users shall give an acknowledgment to the depositors when publishing the research results. contact us |
| Animal Health Report |
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| Strain description |
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| Reference(s) |
- Sassa T, and Kihara A. (2023) Involvement of ω-O-acylceramides and protein-bound ceramides in oral permeability barrier formation. Cell Rep 42(4):112363. [PMID:37054712]
- Tetreault MP, Wang ML, Yang Y, Travis J, Yu QC, Klein-Szanto AJ, and Katz JP. (2010) Klf4 overexpression activates epithelial cytokines and inflammation-mediated esophageal squamous cell cancer in mice. Gastroenterology 139(6):2124-2134.e9. [PMID:20816834]
- Sassa T, Ohno Y, Suzuki S, Nomura T, Nishioka C, Kashiwagi T, Hirayama T, Akiyama M, Taguchi R, Shimizu H, Itohara S, and Kihara A. (2013) Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production. Mol Cell Biol 33(14):2787-96. [PMID:23689133]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
ED-L2-Cre/+ Elovl1 flox/+ |
| Medium |
Fertiup |
| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
IVF |
| Genotype |
ED-L2-Cre/+ or wild-type, Elovl1 flox/+ or wild-type |
| Medium |
EFS40 |
| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
transgenic, knockin |
| Gene symbol |
Elovl1, loxP |
| Gene name |
ELOVL fatty acid elongase 1, locus of X-over P1 |
| Genotyping information |
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