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Strain Detail: FAT-CDO mice
| Strain information |
| Resource No. |
nbio047 |
| Strain name |
FAT-CDO |
| Strain Nomenclature |
|
| Common name/Synonyms |
aP2-CDO mice |
| Strain types |
mutant |
| Background strain |
|
| Institution |
Division of basic nutrition, National Institute of Health and Nutrition |
| Developer |
|
| Depositor |
Nobuyo Kasaoka |
| Conditions of distribution |
It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
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| Strain description |
FAT-CDO mice are transgenic mice overexpressing specifically rat cysteine dioxygenase (CDO) in fat tissue. CDO, a rate-limiting enzyme of taurine synthesis, is expected to promote taurine synthesis in fat tissue. Transgene is designed including aP2 promoter. This strain overexpresses 2-3 times CDO in fat tissue compared with normal mice. This strain are available for research of metabolic syndolome or relationship between taurine and obesity. |
| Reference(s) |
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
|
| Medium |
FERTIUP |
| From other institutions |
Genotype |
|
| Medium |
|
| Cryopreserved embryo |
In-house |
Mating System |
|
| Genotype |
|
| Medium |
EFS40 |
| From other institutions |
Mating System |
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| Genotype |
|
| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
transgenic |
| Gene symbol |
Cdo |
| Gene name |
Cysteine dioxygenase |
| Genotyping information |
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