HOME > mice > L-PGDS-H-PGDS-dKO mice
Strain Detail: L-PGDS-H-PGDS-dKO mice
| Strain information |
| Resource No. |
nbio424 |
| Strain name |
L-PGDS-H-PGDS-dKO |
| Strain Nomenclature |
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| Common name/Synonyms |
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| Strain types |
mutant |
| Background strain |
C57BL/6J |
| Institution |
Center for Supporting Pharmaceutical Education, Daiichi University of Pharmacy |
| Developer |
Yoshihiro Urade |
| Depositor |
Yoshihiro Urade |
| Conditions of distribution |
The user must cite the reference (Ref. 1) provided by the depositors when publishing the research results. contact us |
| Animal Health Report |
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| Strain description |
The double knockout mice lack both lipocalin-type PGD synthase and hematopoietic-type PGD synthase. |
| Reference(s) |
- Kaushik MK, Aritake K, Kamauchi S, Hayaishi O, Huang ZL, Lazarus M, and Urade Y. (2014) Prostaglandin D(2) is crucial for seizure suppression and postictal sleep. Exp Neurol 253():82-90. [PMID:24333565]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
DKO |
| Medium |
Fertiup |
| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
homozygous sperm ｘ C57BL/6J Jcl, & homozygous sperm x heterozygous |
| Genotype |
heterozygous & homozygous |
| Medium |
EFS40 |
| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
dobule knockout |
| Gene symbol |
Ptgds (L-PGDS), Hpgds |
| Gene name |
prostaglandin D2 synthase (brain), hematopoietic prostaglandin D synthase |
| Genotyping information |
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