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Strain Detail: L-PGDS-KO mice
| Strain information |
| Resource No. |
nbio422 |
| Strain name |
L-PGDS-KO |
| Strain Nomenclature |
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| Common name/Synonyms |
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| Strain types |
mutant |
| Background strain |
C57BL/6J |
| Institution |
Center for Supporting Pharmaceutical Education, Daiichi University of Pharmacy |
| Developer |
Yoshihiro Urade |
| Depositor |
Yoshihiro Urade |
| Conditions of distribution |
The user must cite the reference (Ref. 1) provided by the depositors when publishing the research results. contact us |
| Animal Health Report |
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| Strain description |
Lipocalin-type PGD synthase (L-PGDS)-deficient mice (mice in which exons 2-5 of L-PGDS were replaced with a neomycin-resistant gene). |
| Reference(s) |
- Eguchi N, Minami T, Shirafuji N, Kanaoka Y, Tanaka T, Nagata A, Yoshida N, Urade Y, Ito S, and Hayaishi O. (1999) Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice. Proc Natl Acad Sci U S A 96(2):726-30. [PMID:9892701]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
homozygous |
| Medium |
Fertiup |
| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
homozygous sperm x C57BL/6J Jcl |
| Genotype |
heterozygous |
| Medium |
EFS40 |
| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
knockout |
| Gene symbol |
Ptgds (L-PGDS) |
| Gene name |
prostaglandin D2 synthase (brain) |
| Genotyping information |
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