HOME > mice > lox-hyBRET-ERK-NLS-RGECO mice
Strain Detail: lox-hyBRET-ERK-NLS-RGECO mice
| Strain information |
| Resource No. |
nbio434 |
| Strain name |
lox-hyBRET-ERK-NLS-RGECO |
| Strain Nomenclature |
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| Common name/Synonyms |
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| Strain types |
mutant |
| Background strain |
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| Institution |
Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University |
| Developer |
Michiyuki Matsuda |
| Depositor |
Michiyuki Matsuda |
| Conditions of distribution |
It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
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| Strain description |
A mouse expressing a nuclear-localized FRET biosensor monitoring ERK activity and a red calcium sensor under a CAG promoter. The biosensor is not expressed prior to Cre activation, but tissue-specific expression becomes possible through mating with a Cre mouse. For details on the FRET biosensor, please refer to the website of Dr. Matsuda's laboratory. |
| Reference(s) |
- Imanishi A, Ichise H, Fan C, Nakagawa Y, Kuwahara K, Sumiyama K, Matsuda M, and Terai K. (2021) Visualization of Spatially-Controlled Vasospasm by Sympathetic Nerve-Mediated ROCK Activation. Am J Pathol 191(1):194-203. [PMID:33069718]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
Hemizyous |
| Medium |
Fertiup |
| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
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| Genotype |
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| Medium |
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| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
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| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
transgenic |
| Gene symbol |
CFP, YFP, Rluc |
| Gene name |
cyan fluorescent protein, yellow fluorescent protein, Renilla Luciferase |
| Genotyping information |
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