HOME > mice > lox-hyBRET-ERK-NLS mice
Strain Detail: lox-hyBRET-ERK-NLS mice
| Strain information |
| Resource No. |
nbio436 |
| Strain name |
lox-hyBRET-ERK-NLS |
| Strain Nomenclature |
|
| Common name/Synonyms |
|
| Strain types |
mutant |
| Background strain |
|
| Institution |
Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University |
| Developer |
Michiyuki Matsuda |
| Depositor |
Michiyuki Matsuda |
| Conditions of distribution |
It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
|
| Strain description |
Mice expressing a nuclear-localized FRET biosensor for monitoring ERK activity under a CAG promoter. The biosensor is not expressed prior to Cre activation, but tissue-specific expression becomes possible through mating with Cre mice. For details on the FRET biosensor, please refer to the website of the depositor, Dr. Matsuda's Laboratory. |
| Reference(s) |
- Ichise H, Tsukamoto S, Hirashima T, Konishi Y, Oki C, Tsukiji S, Iwano S, Miyawaki A, Sumiyama K, Terai K, and Matsuda M. (2022) Functional visualization of NK cell-mediated killing of metastatic single tumor cells. Elife 11():. [PMID:35113018]
|
| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
Hemizygous |
| Medium |
Fertiup |
| From other institutions |
Genotype |
|
| Medium |
|
| Cryopreserved embryo |
In-house |
Mating System |
|
| Genotype |
|
| Medium |
|
| From other institutions |
Mating System |
|
| Genotype |
|
| Method |
|
| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
|
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
transgenic |
| Gene symbol |
CFP, YFP, Rluc |
| Gene name |
cyan fluorescent protein, yellow fluorescent protein, Renilla Luciferase |
| Genotyping information |
|
