HOME > mice > C57BL/6-Tg(p35/EGFP)Kyo mice
Strain Detail: C57BL/6-Tg(p35/EGFP)Kyo mice
| Strain information |
| Resource No. |
nbio226 |
| Strain name |
C57BL/6-Tg(p35/EGFP)Kyo |
| Strain Nomenclature |
C57BL/6-Tg(p35/EGFP)Kyo |
| Common name/Synonyms |
βMHC-p35 Tg, p35/EGFP |
| Strain types |
mutant |
| Background strain |
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| Institution |
Department of Animal Development and Physiology, Kyoto University |
| Developer |
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| Depositor |
Kazuhiro Sakamaki |
| Conditions of distribution |
In publishing the research results obtained by use of the animal resource, a citation of the following literature (ref.1) and the stipulation of an acknowledgment to depositor designated by the depositor is requested. :contact us |
| Animal Health Report |
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| Strain description |
βMHC-p35 Tg mice are transgenic mice specifically expressing baculovirus p35 and EGFP by mouse βMHC promoter in cardiomyocytes. Baculovirus p35, a caspase inhibitor, is known to stop apoptosis in host cells, thus this strain is useful for the research of apoptosis in cardiomyocytes. |
| Reference(s) |
- Yajima N, Yamada S, Morisaki T, Toyokuni S, Yonehara S, and Sakamaki K. (2005) Partial correction of abnormal cardiac development in caspase-8-deficient mice by cardiomyocyte expression of p 35. Transgenic Res 14(5):593-604. [PMID:16245150]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
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| Medium |
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| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
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| Genotype |
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| Medium |
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| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
transgenic |
| Gene symbol |
Myh7, p35, EGFP |
| Gene name |
[myosin, heavy chain 7, cardiac muscle, beta], p35, Enhanced Green Fluorescent Protein |
| Genotyping information |
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