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Strain Detail: C57BL/6J(V2D) mice
| Strain information |
| Resource No. |
nbio313 |
| Strain name |
C57BL/6J(V2D) |
| Strain Nomenclature |
|
| Common name/Synonyms |
V2D |
| Strain types |
mutant |
| Background strain |
C57BL/6J |
| Institution |
National Cerebral and Cardiovascular Center |
| Developer |
Yuko Iwata |
| Depositor |
Yuko Iwata |
| Conditions of distribution |
Only for collaboration with the depositor: contact us |
| Animal Health Report |
|
| Strain description |
Transient receptor potential cation channel (TRP), subfamily V, member 2 (TRPV2) is a Ca2+-permeable TRP channel. Its pathophysiological roles are still unknown. This strain is a mouse line heterozygous for floxed and wild-type Trpv2 alleles. The floxed alleles, derived from V2K, has been silenced (TRPV2del) by crossing mice with CMV-driven Cre, but no CMV-Cre is left in the strain. Crossing between males and females of this strain produces TRPV2 knock-out mice. |
| Reference(s) |
|
| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
V2(Δ/Δ)及びV2(Δ/W) |
| Medium |
FERTIUP |
| From other institutions |
Genotype |
|
| Medium |
|
| Cryopreserved embryo |
In-house |
Mating System |
IVF |
| Genotype |
heterozygous and wild-type for V2(Δ) |
| Medium |
EFS40 |
| From other institutions |
Mating System |
|
| Genotype |
|
| Method |
|
| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
knockout |
| Gene symbol |
Trpv2 |
| Gene name |
transient receptor potential cation channel, subfamily V, member 2 |
| Genotyping information |
|
