HOME > mice > Ace2-KO x ACE2-Tg#5 mice
Strain Detail: Ace2-KO x ACE2-Tg#5 mice
| Strain information |
| Resource No. |
nbio475 |
| Strain name |
Ace2-KO x ACE2-Tg#5 |
| Strain Nomenclature |
|
| Common name/Synonyms |
|
| Strain types |
mutant |
| Background strain |
C57BL/6N |
| Institution |
Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition |
| Developer |
Osamu Suzuki |
| Depositor |
Osamu Suzuki |
| Conditions of distribution |
Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
|
| Strain description |
A mouse strain lacking endogenous mouse ACE2 and expressing human ACE2. It was created by crossing Ace2-KO (nbio388) and ACE2-Tg#5 (nbio296) mice. This strain is useful for coronavirus disease research. |
| Reference(s) |
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
KO/Tg |
| Medium |
Fertiup |
| From other institutions |
Genotype |
|
| Medium |
|
| Cryopreserved embryo |
In-house |
Mating System |
IVF |
| Genotype |
KO/Tg |
| Medium |
EFS40 |
| From other institutions |
Mating System |
|
| Genotype |
|
| Method |
|
| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
knockout and transgenic (hybrids) |
| Gene symbol |
Ace2 |
| Gene name |
Angiotensin-converting enzyme 2 |
| Genotyping information |
|
