HOME > mice > NDRG1flox mice
Strain Detail: NDRG1flox mice
| Strain information |
| Resource No. |
nbio063 |
| Strain name |
NDRG1flox |
| Strain Nomenclature |
C57BL/6CrSlc-TgH(Ndrg1)Flox114 NCVC |
| Common name/Synonyms |
|
| Strain types |
mutant |
| Background strain |
|
| Institution |
National Cerebral and Cardiovascular Center Research Institute |
| Developer |
Toshiyuki Miyata |
| Depositor |
Toshiyuki Miyata (Contact person: Koichi Kokame) |
| Conditions of distribution |
It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
|
| Strain description |
NDRG1flox mice are introduced three loxP sites flanking exon 1 of NDRG1 gene and neomycin resistant gene cassette. This strain is possible to delete NDRG1 gene by crossing with Cre expressing mice. It's possible to inactivate NDRG1 stage- or tissue-specifically by selecting different promoter inducing to express Cre recombinase. Please refer to section ofNDRG1 KOmice (nbio062). |
| Reference(s) |
- Okuda T, Higashi Y, Kokame K, Tanaka C, Kondoh H, and Miyata T. (2004) Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves. Mol. Cell. Biol. 24(9):3949-56. [PMID:15082788]
|
| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
|
| Medium |
FERTIUP |
| From other institutions |
Genotype |
|
| Medium |
|
| Cryopreserved embryo |
In-house |
Mating System |
|
| Genotype |
|
| Medium |
EFS40 |
| From other institutions |
Mating System |
|
| Genotype |
|
| Method |
|
| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
