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List of mice by affected organs: Mus musculus
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As of Sept. 25th, 2006:
| Affected organ | Diseases | Genetic info | Strain name |
|---|---|---|---|
| Heart | Dilated cardiomyopathy | Overexpression of β-galactoside α-2,3-sialyltransferase2 transgene | 4C30 |
| Kidney | Hereditary nephrosis | Mutant from Yok:ICR, mutation in tensin2 gene | ICGN |
| Lupus glomerulonephritis | Ectopic expression of CD40 ligands on B cells | CD40L | |
| Lung | Susceptible to Mycoplasma infection | Mutant from Yok:ICR | MPS |
| Skin/coat | Poor coat, swelling of lymph nodes | Spontaneus mutants, mutation in Sgk3/Sgkl/CISK gene | YPC |
| Alopecia | Spontaneus mutants | HR | |
| Brain | Epilepsy | Spontaneus mutants | EL |
| Lysosomal diseases | Acid β-galactosidase knockout mice | BKO | |
| Overexpression of human mutant β-galactosidase (I51T) without mouse endogenous β-galactosidase | AK | ||
| Overexpression of human mutant β-galactosidase (R201C) without mouse endogenous β-galactosidase | BK | ||
| Overexpression of human normal β-galactosidase | CG | ||
| Overexpression of human normal β-galactosidase without mouse endogenous β-galactosidase | CK | ||
| Overexpression of human mutant β-galactosidase (I51T) | GalA | ||
| Overexpression of human mutant β-galactosidase (R201C) | GalB | ||
| Overexpression of mouse GM1/GA1 synthase (β1,3-Galactosyltransferase) | GM1sy | ||
| Bone/Cartilage | Morquio B disease | Overexpression of human mutant β-galactosidase (W273L) | GalF |
| Immune system | Systemic Lupus Erythematosus (SLE) | Ectopic expression of CD40 ligands on B cells | CD40L |